Can Magnesium Glycinate Cause Acne

Can Magnesium Glycinate Cause Acne?

Magnesium glycinate is a type of magnesium mineral that is often used as a dietary supplement. It is composed of magnesium and glycine, an amino acid. Magnesium glycinate is known for its high absorption and bioavailability, making it a popular form of magnesium supplementation. It is generally considered safe with a low risk of side effects. However, some individuals may experience acne breakouts as a potential side effect of taking magnesium glycinate.

Possible Reasons for Acne Breakouts:

  1. Histidine Metabolism: Magnesium glycinate can interfere with the metabolism of histidine, an amino acid involved in skin health. This disruption can lead to an increase in sebum production, which can contribute to acne.

  2. Hormonal Imbalance: Some studies suggest that magnesium glycinate may affect hormonal balance in certain individuals, potentially leading to hormonal acne. However, more research is needed to fully understand this connection.

  3. Individual Sensitivity: Some individuals may have a heightened sensitivity to magnesium glycinate, making them more prone to acne breakouts. This sensitivity could be due to individual differences in skin physiology and response to certain supplements.

Managing Acne while Taking Magnesium Glycinate:

  1. Monitor Dosage and Timing: If you experience acne breakouts after starting magnesium glycinate, consider adjusting the dosage or timing of your supplement intake. Reducing the dose or taking it at different times of the day may help minimize the impact on your skin.

  2. Consult a Healthcare Professional: It is essential to consult with a healthcare professional or dermatologist if you are concerned about acne breakouts related to magnesium glycinate. They can provide guidance on dosage adjustments or alternative magnesium sources that may be better suited for your individual needs.

  3. Alternative Magnesium Forms: If acne persists despite dosage adjustments, you may consider trying other forms of magnesium, such as magnesium citrate or magnesium malate. These forms have different absorption rates and mechanisms of action, which may be less likely to cause acne breakouts.

  4. Dietary Changes: Incorporating a balanced diet rich in fruits, vegetables, and whole grains can support overall skin health. Limiting processed foods, sugary drinks, and excessive dairy products may also help improve acne-prone skin.


While magnesium glycinate is generally well-tolerated, some individuals may experience acne breakouts as a potential side effect. If you notice acne developing after starting magnesium glycinate supplementation, consider adjusting the dosage, timing, or consulting a healthcare professional for guidance. Managing acne while taking magnesium glycinate may involve finding a suitable dosage, trying alternative forms of magnesium, adopting a healthy diet, and working with a dermatologist if needed. It is important to remember that everyone’s body responds differently to supplements, and what works for one person may not work for another.