Does Amyloidosis Cause Hair Loss

Hair Loss and Amyloidosis: A Complex Relationship

While amyloidosis is not a direct cause of hair loss, there are situations where it can be connected. Here’s a breakdown of the relationship:

1. Amyloidosis itself:

  • Amyloidosis is a rare disease characterized by abnormal protein deposits called amyloid in various organs.
  • In most cases, hair loss is not a typical symptom of amyloidosis.

2. Amyloidosis and Skin Involvement:

  • Some types of amyloidosis, especially those associated with plasma cell dyscrasias like multiple myeloma, can affect the skin.
  • In these cases, amyloid deposits can sometimes involve hair follicles, leading to localized or even diffuse hair loss.
  • This hair loss is not a common symptom but can occur in a small percentage of patients.

3. Additional Factors:

  • Certain treatment options for amyloidosis, like chemotherapy, can cause temporary hair loss as a side effect.
  • Other underlying conditions or nutritional deficiencies associated with amyloidosis might also contribute to hair loss.


  • It’s essential to understand that amyloidosis alone does not typically cause hair loss.
  • If you experience hair loss alongside other symptoms, it’s crucial to consult your doctor for a thorough evaluation.
  • The doctor can identify the underlying cause of hair loss and determine the best course of action based on your specific situation.


  • This information is not a substitute for professional medical advice.
  • Always consult your doctor for any health concerns you may have.

I hope this explanation clarifies the connection between amyloidosis and hair loss. Feel free to ask any further questions you might have.