Does Keppra Cause Acne

Does Keppra Cause Acne?

There is no definitive answer to whether Keppra (levetiracetam) directly causes acne. While acne is not listed as a common side effect in official sources like the FDA-approved prescribing information or the Mayo Clinic, anecdotal evidence suggests some people experience breakouts after starting Keppra.

Here’s what we know:

  • Limited Research: Studies haven’t conclusively established a link between Keppra and acne. Some small studies haven’t found a significant association, while others mention acne as a reported side effect but without firm data.
  • Individual Reactions: People react differently to medications, and what affects one person might not affect another. Some individuals may be more prone to Keppra-related acne due to underlying skin conditions or hormonal factors.
  • Hormonal Impact: Keppra can affect certain hormones, potentially leading to increased oil production and clogged pores, which could contribute to acne.
  • Other Factors: Acne can have many causes, making it difficult to pinpoint Keppra as the sole culprit. Lifestyle factors like diet, stress, and skincare routine can also play a role.

What to do if you suspect Keppra-related acne:

  • Consult your doctor: If you develop new or worsening acne after starting Keppra, talk to your doctor. They can assess your situation, consider other potential causes, and recommend treatment options for your acne.
  • Track your symptoms: Keep a diary to track your skin changes, medication dosage, and any other relevant factors like dietary changes or stress levels. This information can help your doctor make informed decisions.
  • Explore alternative treatments: If acne is bothersome and Keppra is suspected to be the cause, your doctor may discuss adjusting your medication or trying other acne treatments alongside Keppra.


  • Never stop or adjust your Keppra dose without consulting your doctor.
  • Acne is a common skin condition with many potential causes.
  • Individual experiences with Keppra can vary.
  • If you’re concerned about acne, talk to your doctor. They can help you manage your skin health while controlling your epilepsy.

It’s important to seek professional medical advice for any concerns about medication side effects, including potential Keppra-related acne. Your doctor can help you navigate the situation and find the best approach for your individual needs.